![]() They’re going to get more powerful,” says Baker. “The methods are already really powerful. Among the companies that are working towards this goal are DeepMind in London and Meta (formerly Facebook) in Menlo Park, California. But researchers - and a growing number of companies that are applying AI to protein design - would like to design proteins that can do useful things, from cleaning up toxic waste to treating diseases. Most efforts are focused on tools that can help to make original proteins, shaped unlike anything in nature, without much focus on what these molecules can do. “Since AlphaFold, there’s been a shift in the way we work with protein design,” says Noelia Ferruz, a computational biologist at the University of Girona, Spain. Previously, this had been a painstaking pursuit with high failure rates. And recent months have seen an explosive growth in AI tools - some based on AlphaFold - that can quickly dream up completely new proteins. In July, DeepMind revealed that the latest version of AlphaFold had predicted structures for every protein known to science. Franky impact client software#Such efforts are a part of a scientific sea change, as AI tools such as DeepMind’s protein-structure-prediction software AlphaFold are embraced by life scientists. ‘The entire protein universe’: AI predicts shape of nearly every known protein Now, thanks to gargantuan advances in artificial intelligence (AI), a team led by David Baker, a biochemist at the University of Washington (UW) in Seattle, reports in Science 2, 3 that it can design such molecules in seconds instead of months. The vaccine is based on a spherical protein ‘nanoparticle’ that was created by researchers nearly a decade ago, through a labour-intensive trial-and error-process 1. ![]() ![]() In June, South Korean regulators authorized the first-ever medicine, a COVID-19 vaccine, to be made from a novel protein designed by humans. Credit: Ian C Haydon/UW Institute for Protein Design Artificial-intelligence tools are helping to scientists to come up with proteins that are shaped unlike anything in nature. ![]()
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